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Chinese Blistering Beetle, Mylabris phalerata Pallas and M. cichodi L. Cantharis Family Meloidae.
Administration Decoction or pill (powder): 0.3-1.0g Cantharidin tablet: 0.5mg gradually increased to 2-4mg once daily, totally 240mg as 1 course. Cantharidin ampoule: 0.25mg gradually increased to 2mg IM once daily, 1-3 months as 1 course. Hydroxy-cantharidamine tablet: 50-100mg tid. The latter three preparations are only used for tumours.
Caution All preparations of Chinese blister beetle are strong poisons, which may cause nephritis, cystitis, burning sensation of digestive tract, vomiting, palpitation and numbness of fingers. External use may cause local congestion, vesiculation, burning pain, and also toxic effect through absorption. So the dosage (both oral and topical use) should be limited. It is contraindicated for the cases with cardiac, renal and gastrointestinal diseases, and should be taken after meals. Toxic and side effects may be ameliorated if the drug is taken with green tea, diuretics or stomachics. Links
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